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The Science Behind Kurva Pro

A next generation of strains shaping how the gut regulates fat and metabolism

A pioneer class of probiotic strains, rooted in South Korean fermentation research and refined through a patented isolation process.

Each strain was selected for a specific biological role and studied for its interaction with metabolic signaling related to body composition and fat storage.


Kimchi-Derived Metabolic Origins

Identified from traditional South Korean fermentation, representing a foundational food-based research origin.

Lean-Gut Profile Models

Engineered to replicate gut microbiome profiles observed in naturally lean individuals shaped by lifelong fermented-food diets.

The Journey Behind These Strains

Traditional South Korean Fermentation

The starting point: generations of kimchi fermentation that shaped daily diets and long-term metabolic patterns.

Traditional South Korean Fermentation

Microbial Identification

Across two converging sources, traditional kimchi fermentation + the gut profiles of women shaped by lifelong kimchi consumption, distinct microbial strains were identified for consistent metabolic relevance in populations known for stable weight regulation.

Microbial Identification

Patented Isolation Process

Individual microbes were isolated and refined through a patented extraction process to evaluate specific biological roles rather than broad probiotic activity.

Patented Isolation Process

Scientific Evaluation

Refined strains, including HY7601, KY1032, MG4231, and MG4244, were evaluated through controlled research to examine their role in metabolic signaling, gut function, and fat-related pathways.

Scientific Evaluation

Controlled U.S. Production

The selected cultures are transferred to U.S. based, NSF-certified facilities, where independently verified quality and purity standards regulate production to protect strain identity, consistency, and integrity from research through daily use.

Controlled U.S. Production

Traditional South Korean Fermentation

The starting point: generations of kimchi fermentation that shaped daily diets and long-term metabolic patterns.

Discovery in Diet and Biology

Across two converging sources, traditional kimchi fermentation + the gut profiles of women shaped by lifelong kimchi consumption, distinct microbial strains were identified for consistent metabolic relevance in populations known for stable weight regulation.

Patented Isolation Process

Individual microbes were isolated and refined through a patented extraction process to evaluate specific biological roles rather than broad probiotic activity.

Scientific Evaluation

Refined strains, including HY7601, KY1032, MG4231, and MG4244, were evaluated through controlled research to examine their role in metabolic signaling, gut function, and fat-related pathways.

Controlled U.S. Production

The selected cultures are transferred to U.S. based, NSF-certified facilities, where independently verified quality and purity standards regulate production to protect strain identity, consistency, and integrity from research through daily use.


Scientific Collaboration

Kurva Pro was developed in collaboration with microbiome researchers responsible for the discovery, isolation, and formulation of Lactobacillus curvatus HY7601, Lactobacillus plantarum KY1032, and the Limosilactobacillus fermentum strains MG4231 and MG4244 - working across traditional fermentation systems, human gut profiling, and laboratory validation.

Gut Signal Restoration™

Metabolic regulation doesn’t start with calories or willpower. It begins with signals in the gut that help guide how energy is stored, used, and released throughout the body.

Rather than targeting isolated symptoms, ēvene’s science focuses on restoring these underlying communication pathways between the gut and metabolic function - a system level approach known as Gut Signal Restoration™ (GSR).

Our Research

Human research on these probiotic strains examined how they interact with gut and metabolic signaling systems related to fat storage, utilization, and energy balance over time.

Strains Evaluated

Defined probiotic strains studied in human trials include:

  • Lactobacillus curvatus HY7601
  • Lactobacillus plantarum KY1032
  • Limosilactobacillus fermentum MG4231
  • Limosilactobacillus fermentum MG4244

These were assessed both individually and in defined combinations to better understand their biological roles and interactions.

Fat & Metabolic Measures Assessed

Evaluation focused on objective markers related to fat regulation and metabolic signaling, including:

  • Body composition measures such as fat mass, fat distribution, and waist circumference
  • Biomarkers associated with lipid metabolism, including triglycerides
  • Indicators linked to cellular energy regulation pathways
Gut Microbiome Measures

Research also examined how these strains interact with the gut environment, including:

  • Changes in gut microbiome composition and structure
  • Shifts in bacterial groups associated with metabolic signaling and gut function

This analysis focused on biological patterns rather than symptom-based endpoints.

Study Design Overview

Several studies were conducted using structured human research designs, including randomized and placebo-controlled formats over multi-week periods. Outcomes were assessed using standardized clinical and laboratory measurements.

Published Scientific Research

The probiotic strains and prebiotic components used in ēvene’s formulations have been examined in peer-reviewed scientific research published in recognized academic journals.

The publications below provide direct access to the original studies, including methodology, study design, and measured outcomes.

Peer-Reviewed Scientific Publications  >>


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